This suggests that the EGFR–ARFGEP100–ARF6 pathway might be activated in breast cancer cells that acquire a malignant phenotype. Finally, the authors showed that silencing ARFGEP100 in a mouse ...

Assessment of transfer entropy is useful for network analysis of cell signaling network providing information on the network topology and action points of genetic mutations and drug effect, thus will ...

Targeted therapies are one of the latest innovative trends in cancer therapy. The epidermal growth factor receptor (EGFR) is a target found in high concentrations in several solid tumors including ...