Testing experimental cancer drugs in mouse models with patient-derived tumors could reduce the high failure rate of drugs in early clinical trials, according to a new report. Testing experimental ...

Cancer remains one of the most pressing global health challenges, with millions of new diagnoses each year. While precision ...

In addition, the team built a computational model that can simulate the force imbalances present in heterogenous cell pairs of both murine and human stem cell-derived cardiomyocytes. "This work is ...

New review highlights how mini-organs model tumor environments, enhance drug testing, and pave the way for personalized cancer treatments. Study: Patient-derived organoids in precision cancer ...

“This stem cell-derived model of dry AMD is a game-changer ... among other biological functions. To test this hypothesis, the researchers exposed 10 iPSC-derived RPE cell lines involving ...

Researchers use human induced pluripotent stem cell (iPSC)-derived models to create genetically accurate disease models for which genotype and phenotype are closely matched. However, this process can ...

With advances in patient-derived iPSCs and organ-on ... Dynamic42 created a pancreatic cancer chip model, which showed promising results in testing MSD’s FDA-approved therapy Zolinza (vorinostat).

Our wet and dry lab teams have been working together to generate single-cell -omics data from clinical specimens and our patient-derived models, perform informatics analyses to generate new hypotheses ...

has for the first time developed an organoid model of human pluripotent stem cell-derived pancreatic islets (SC-islets) with integrated vasculature. Researchers in the Sander lab at the University ...