Testing experimental cancer drugs in mouse models with patient-derived tumors could reduce the high failure rate of drugs in early clinical trials, according to a new report. Testing experimental ...

Cancer remains one of the most pressing global health challenges, with millions of new diagnoses each year. While precision ...

In addition, the team built a computational model that can simulate the force imbalances present in heterogenous cell pairs of both murine and human stem cell-derived cardiomyocytes. "This work is ...

New review highlights how mini-organs model tumor environments, enhance drug testing, and pave the way for personalized cancer treatments. Study: Patient-derived organoids in precision cancer ...

“This stem cell-derived model of dry AMD is a game-changer ... among other biological functions. To test this hypothesis, the researchers exposed 10 iPSC-derived RPE cell lines involving ...

Researchers use human induced pluripotent stem cell (iPSC)-derived models to create genetically accurate disease models for which genotype and phenotype are closely matched. However, this process can ...

With advances in patient-derived iPSCs and organ-on ... Dynamic42 created a pancreatic cancer chip model, which showed promising results in testing MSD’s FDA-approved therapy Zolinza (vorinostat).

Our wet and dry lab teams have been working together to generate single-cell -omics data from clinical specimens and our patient-derived models, perform informatics analyses to generate new hypotheses ...

Hesperos and UCF researchers developed a co-culture model using iPSC-derived Schwann cells and ... replace and refine alternatives to animal testing and accelerate drug discovery with novel ...

has for the first time developed an organoid model of human pluripotent stem cell-derived pancreatic islets (SC-islets) with integrated vasculature. Researchers in the Sander lab at the University ...