Watson and Crick's discovery of DNA structure ... replication. So why didn't Meselson and Stahl finally explain this mechanism until 1958? Semiconservative replication was not the only model ...

Scientists say their work on a critical step in DNA replication ... study (“Cryo-EM Structure of Mcm2-7 Double Hexamer on DNA Suggests a Lagging-Strand DNA Extrusion Model”) in PNAS.

Replication of cellular ... resolution (see Methods). Figure 1: Structure of the prim-pol domain. To gain support for this model of prim-pol domain–DNA interaction, we mutated conserved residues ...

They first determined the structure of the "Origin Recognition Complex" (ORC), a protein that identifies and attaches to specific DNA sites to initiate the entire replication process. The second ...

Tracking viral DNA in the cell: New method to generate virus particles containing labeled viral DNA genomes. ScienceDaily . Retrieved May 19, 2025 from www.sciencedaily.com / releases / 2013 / 10 ...