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Our complex genetic information can be sliced in many ways, but one common divisor is between coding and non-coding DNA. As their name suggests, only coding regions are later transcribed into RNA and ...
Sorting through non-coding DNA to find the root of chemotherapy resistance "The non-coding 98% of the genome contains instructions," said co-first author Jackson Mobley, Ph.D., St. Jude Department ...
Only 2% of human DNA contains the 'code' to produce proteins, key building blocks of life. The remaining 98% is 'non-coding' and was once thought to be unnecessary 'junk' DNA, but there is ...
Much of the "junk" DNA in Drosophila shows signs of either negative or positive selection, according to a study in this week's Nature. An analysis by Peter Andolfatto of the University of California, ...
For many years, it was easier for scientists to simply ignore all of that extra genetic material, and it was written off as junk DNA that served no purpose. But in recent decades, the importance of ...
Comparisons of human chromosome 19 and mouse DNA sequences confirm extensive coding and non-coding conservation with 4,586 discrete fragments showing conservation (> 70% identity with a score of ...
The findings, which highlight the importance of non-coding regions of DNA, have been reported in the New England Journal of Medicine. Only about two percent of the human genome codes for protein, and ...
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The mechanism reveals that damages to non-coding DNA, which are often hidden, accumulate more in slowly proliferating tissues ...
Non-coding DNA variants contribute to acute lymphoblastic leukemia (ALL) chemotherapy resistance. St. Jude Children's Research Hospital scientists have identified specific DNA variants in the non ...
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