factors in the clotting cascade, patients have an increased risk of bleeding with invasive procedures. Patients also have an increased risk of developing a thromboembolism if these drugs are ...

Vitamin K antagonists, such as warfarin, have an unpredictable pharmacokinetic profile and numerous food and drug interactions ... key proteases in the coagulation cascade: thrombin and factor ...

without affecting other elements of the clotting cascade that can lead to bleeding side effects. TargED intends to go after aTTP in its initial clinical development programme for the new drug, but ...

Coagulant Therapeutics—a privately held biotech company of seasoned drug developers specializing in biologics and the coagulation cascade—is here to fill that void. Drawing on over 100 years ...