In the study, investigators utilized nanoscale imaging and sensing technologies along with modeling techniques developed at Northwestern to individually label and observe chromatin fibers ...

In eukaryotes, DNA is tightly wound into a complex called chromatin. Thanks to the process of chromatin remodeling, this complex can be "opened" so that specific genes are expressed. Various ...

View Full Profile. Learn about our Editorial Policies. Lis and Gilmour focused on identifying proteins that bound to specific chromatin sites to understand the mechanisms of gene regulation. To do so, ...

When genes are coiled and compacted into chromatin, they're no longer accessible to transcription factors. So how does the cell know where to uncoil in a process called chromatin remodeling?

Parse’s chromatin accessibility technology leverages a novel approach with advantages over existing methods such as ATAC-seq and will deliver higher quality, more uniform data. Parse plans to ...

But truly understanding these effects requires a deeper look into chromatin regulation and epigenetic mechanisms. In this GEN webinar, our expert speaker Dave Lahr, PhD, Senior Director of ...

Innovative research approaches are therefore urgently needed to achieve long-term progress in prevention and ...

Hepatitis B virus infection remains one of the leading causes of liver disease, including cirrhosis and hepatocellular carcinoma.

We specialize in high throughput top down liquid chromatography-mass spectrometry. This allows us to study chromatin biology with proteoform level specificity and observe quantitative changes to ...

Mammalian genomes are organized by multi-level folding, yet how this organization contributes to cell type-specific transcription remain unclear. We uncovered that the nuclear protein SATB1 ...