Thus, our data indicate that, unlike its proximal role in receptor signaling, in the mitochondrial pathway caspase-8 rather functions as an amplifying executioner caspase. In the present study we ...

yielding new knowledge about caspase function as well as insights into the causes of human infertility. Cell death caspases, when activated, were thought to condemn a cell to certain death.

and how those processes (like caspase function) can adapt based on context. As a species, we're pretty good at fixing ourselves up, but we could do better, especially as we get older. It's ...

Similarly, some Alzheimer disease researchers are teasing out the biological function of amyloid precursor protein ... to form a gene-silencing complex that binds caspase-4. In the study, AD appears ...