In fact, it’s possible that the deletion of the gene, called CCR5, might have actually made them smarter than they would otherwise have been, but it will be some time before we know for sure.

That is, except for the work of Dr. He Jiankui. He claims to have used Crispr to target and knock out the CCR5 gene in human embryos, which is linked to HIV infection. And then he did something ...

Dr He used CRISPR or Cas9, which stands for CRISPR-associated protein 9, to target a gene called CCR5, which codes for a protein used by the human immunodeficiency virus-1 (HIV-1) to enter cells.

Following a northern European poxvirus outbreak centuries ago, a 32-base pair deletion in the CCR5 gene became established in the population. This protective mutation persists today. It affords ...

To probe the specific genetic variants or alleles on chromosome 3 and their ... of the four introgressed alleles significantly altered the expression of CCR1 and CCR5, genes that code for key ...

Two more people have been potentially cured of HIV after receiving stem cell transplants to treat blood cancer or bone marrow ...

Researchers are therefore exploring other ways to protect cells from HIV, including using CRISPR gene editing to disable or delete CCR5 receptors on immune cells. But there is an urgent need for ...

Summary: Maraviroc is the first CCR5 coreceptor antagonist to receive marketing approval from the Food and Drug Administration (FDA) for the treatment of CCR5-tropic human immunodeficiency virus ...

HIV-1 entry into cells is an attractive target for new antiviral agents. But will inhibitors aimed at the CCR5 co-receptor force HIV-1 to evolve more virulent forms? Other targets for entry ...

Observations in the viremic non-progressor omics VNPs were more likely to carry one copy of the gene CCR5 with a Δ32 deletion and one copy without (53.8% heterozygosity) compared to progressors ...

These sites bind to coreceptor CCR5 or CXCR4 on the membrane of the host cell (center panel), an event that initiates steps that culminate in the fusion of the HIV envelope with the host cell ...