From the MIT Technology Review story: New research shows that the same alteration introduced into the girls’ DNA, to a gene called CCR5, not only makes mice smarter but also improves human brain ...

That is, except for the work of Dr. He Jiankui. He claims to have used Crispr to target and knock out the CCR5 gene in human embryos, which is linked to HIV infection. And then he did something ...

Following a northern European poxvirus outbreak centuries ago, a 32-base pair deletion in the CCR5 gene became established in the population. This protective mutation persists today. It affords ...

To probe the specific genetic variants or alleles on chromosome 3 and their ... of the four introgressed alleles significantly altered the expression of CCR1 and CCR5, genes that code for key ...

Dr He used CRISPR or Cas9, which stands for CRISPR-associated protein 9, to target a gene called CCR5, which codes for a protein used by the human immunodeficiency virus-1 (HIV-1) to enter cells.

Two more people have been potentially cured of HIV after receiving stem cell transplants to treat blood cancer or bone marrow ...

These sites bind to coreceptor CCR5 or CXCR4 on the membrane of the host cell (center panel), an event that initiates steps that culminate in the fusion of the HIV envelope with the host cell ...

Observations in the viremic non-progressor omics VNPs were more likely to carry one copy of the gene CCR5 with a Δ32 deletion and one copy without (53.8% heterozygosity) compared to progressors ...

Blocking G i protein–coupled receptor signaling by pertussis toxin as well as deficiencies in Gα i2, chemokine receptor 2 (CCR2), CCR5, chemokine ligand 2 (CCL2, also known as monocyte ...

The scientist claimed the modifications would make the children immune to HIV by turning a gene called CCR5 into a mutant form that prevents the virus from invading cells. As genetic engineering ...

Summary: Maraviroc is the first CCR5 coreceptor antagonist to receive marketing approval from the Food and Drug Administration (FDA) for the treatment of CCR5-tropic human immunodeficiency virus ...