We review here findings for the CCL2-CCR2 and CCL3-CCR5 chemokine-receptor systems that show the effects of these molecules on T cell differentiation. Possible roles of other chemokines and G ...
Cenicriviroc is a first-in-class inhibitor of the CCR5 and CCR2 receptors that recently completed Phase II evaluation. This drug is promising because of the possibility that CCR2 inhibition may ...