Blocking G i protein–coupled receptor signaling by pertussis toxin as well as deficiencies in Gα i2, chemokine receptor 2 (CCR2), CCR5, chemokine ligand 2 (CCL2, also known as monocyte ...
Cenicriviroc is a first-in-class inhibitor of the CCR5 and CCR2 receptors that recently completed Phase II evaluation. This drug is promising because of the possibility that CCR2 inhibition may ...
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