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The complement system plays a part in glomerular disease. There are two main forms of glomerular disease: dense deposit disease and C3 glomerulonephritis. Learn more about them both.
Complement component 3, often called C3, is an essential protein of the immune system. This protein plays a vital role in the body’s innate immune system, providing: the first line of defense ...
Chronic kidney disease affects approximately 10% of the Western population. Recent studies have elucidated some of the immune mechanisms that contribute to kidney injury and disease, which are ...
The “classical” pathway of the complement system is triggered when C1q binds to antibodies that are already bound to antigens on a cell surface.
The complement system consists of a number of small proteins found in the blood, in general synthesized by the liver, and normally circulating as inactive precursors (pro-proteins). When stimulated by ...
After a slow start, the race is on to inhibit key proteins and pathways within the complement system -- a biological cascade that is central to the innate immune system and many different diseases ...
Researchers have identified a blood protein ‘signature’ in the complement system, part of the immune system, of patients with long COVID that may improve the diagnosis and lead to a treatment ...
The complement system is composed of more than 30 proteins produced by the liver that travel the bloodstream and act as an immune surveillance system.
Researchers in the United States have conducted a study showing that activation of the complement system is specifically implicated in the pathogenesis of severe coronavirus disease 2019 (COVID-19 ...
A new analysis of lung epithelial cells from COVID-19 patients reveals how the protective complement branch of the immune system, which usually plays roles in both innate and adaptive immunity ...
The complement system is a part of the immune system that enhances (complements) the ability of antibodies and phagocytic cells to clear microbes and damaged cells from an organism, promotes ...