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Array CGH has been implemented using a wide variety of techniques. The initial approaches used arrays with elements produced by spotting DNA obtained directly from large-insert genomic clones such ...
Comparative Genomic Hybridization (CGH) is a powerful technique employed in modern genomics to detect chromosomal gains and losses across the whole genome.
In array CGH, the control or reference genome and the patient’s genome are differentially fluorescently labeled and competitively hybridized to several hundreds or thousands of DNA targets.
We have developed an array CGH analysis system (consisting of an array CGH chip plus its exclusive analysis software) for constitutional genetic diagnosis and have evaluated the suitability of our ...
infoQuant Ltd brings microarray technology closer to clinical use with its latest release of copy number analysis and interpretation software oneClickCGH and CGH Fusion for microarray-based ...
In this study we have used high-resolution genome-wide DNA copy number screening by array-based comparative genomic hybridization (array CGH)2-3 to identify the underlying genetic cause of this ...
Microarray based comparative genomic hybridisation (array CGH) is a new technology with uses developing in various diagnostic areas within the NHS. One important context is the investigation of ...
They recommended that advanced genomic technologies, such as array CGH, be broadly deployed by cell culture banks to ensure consistency of the cells they provide to the research community.
Moreover, when CNVs are suspected, custom array CGH can detect the exact range of CNVs. These genetic analysis tools have enabled us to diagnose almost all inherited kidney diseases.
Conclusion In conclusion, a large spectrum of genomic imbalances, including novel recurring changes in AML with complex karyotypes, was identified using array-CGH. In addition, the combined analysis ...