Background: The Food and Drug Administration-approved argatroban dose for heparin-induced thrombocytopenia (HIT) is 2 µg/kg/min (0.5 µg/kg/min in hepatic impairment), adjusted to achieve ...

There is no known reversal agent for argatroban. The package insert recommends "symptomatic and supportive therapy." [5] With FFP, the coagulation parameters returned to the baseline level of ...