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There are patients with borderline anemia, but with marked microcytosis and normal iron studies and normal HbA2, who are suspected of having alpha thalassemia.
α-thalassemia trait may be difficult to diagnose with certainty after the ... D. J. Relationship of hemoglobin Bart's and H Lo alpha thalassemia. Ann. New York Acad. Sc. 119:463–473, 1964 ...
HYDROPS fetalis associated with hemoglobin Barts is believed to represent the homozygous state of α thalassemia. Ten cases occurring in Chinese families in Indonesia, Malaya and Hong Kong, 1 in a ...
Today new and updated data from bluebird bio inc.’ s gene therapy programs in beta-thalassemia and sickle cell disease were presented at the 64 th American Society of Hematology Annual Meeting ...
“The bottom line is both of these patients have the alpha-thalassemia trait, and because of that they started out being anemic and they continue to be anemic after therapy,” said Colvin, who ...
Bluebird said its investigation showed that patients with persistent anemia had a genetic trait called the alpha-thalassemia trait. Such patients would be excluded from future studies of the drug.