Controlling regioselectivity remains one of the major challenges in hydrocyanation. When an unsymmetrical alkyne undergoes ...

A controlled/“living” click polymerization method developed by researchers at Institute of Science Tokyo and Nagoya University enables precise chain-growth of AB-type monomers—traditionally limited to ...

Buttoned up biomolecules Click reaction for living systems: Bioorthogonal hydroamination of activated linear alkynes Date: June 30, 2021 Source: Wiley ...

However, this reaction requires a toxic copper catalyst, making it unsuitable for living systems. An alternative is the use of cyclic alkynes, in which the triple bond is under so much strain that ...