Computer modeling and simulations were essential to this study. "Using these techniques, we observed that we could recapitulate the characteristic distribution of DNA methylation seen in mammalian ...

Two new landmark studies show how a seeming tangle of DNA is actually organized into a structure that coordinates thousands of genes to form a sperm cell. The work, published March 3 as two papers in ...

Structure of the Mon1-Ccz1 complex reveals molecular basis of membrane binding for Rab7 activation. Proceedings of the National Academy of Sciences , 2022; 119 (6): e2121494119 DOI: 10.1073/pnas ...

A combination of molecular methods and computational modeling has now been used to reconstruct accurate 3D structures of the genome inside single nuclei. You have full access to this article via ...

Researchers at Washington University School of Medicine in St. Louis have revealed the structure of a key protein involved in ...

Germany, have developed a new method that makes it possible for the first time to image the three-dimensional shape of ...

Researchers at Harvard Medical School have combined histology with cutting-edge single-cell imaging technologies to create large-scale 2D and 3D spatial maps of colorectal cancer. The maps layer ...

Molecular 3D structure of viral 'copying machine' deciphered by Lena Bösch, Universitätsmedizin Göttingen - Georg-August-Universität ...

In a recent study by the team, they discovered the 3D structure of a protein called TnpB, a probable precursor to the CRISPR-Cas12 enzyme. Their findings appeared in the journal Nature .

Editor-in-Chief, Francesca Lake, speaks to Jayne Hesley and Jeff McMillan of Molecular Devices to discuss 3D cultures, why they are not yet in widespread use and their future. Jayne Hesley Jayne ...