Scientists have made a major breakthrough in chemical synthesis that now makes it possible to quickly and reliably modify the 3D structure of molecules used in drug discovery. The new method ...

A new study has revealed for the first time the molecular structure of brains affected by Alzheimer's disease. Researchers have produced 3D models of proteins in the brain, including two proteins ...

Molecular 3D structure of viral 'copying machine' deciphered. by Lena Bösch, Universitätsmedizin Göttingen - Georg-August-Universität ...

LMU researchers have developed a super-resolution microscopy method for the rapid differentiation of molecular structures in 3D. Super-resolution microscopy methods are essential for uncovering ...

Using cryo-electron microscopy, the researchers obtained the 3D structures of human ABCC4 in its apo form (without ligand), bound to three different substrates (the TXA 2 analog U46619, aspirin ...

Computer modeling and simulations were essential to this study. "Using these techniques, we observed that we could recapitulate the characteristic distribution of DNA methylation seen in mammalian ...

New drug discovery has long been limited by researchers’ inability to precisely control the 3D structure of molecules. But a team led by scientists from The Graduate Center of The City University of ...

New drug discovery has long been limited by researchers’ inability to precisely control the 3D structure of molecules. But a team has made a major breakthrough in chemical synthesis that now makes it ...